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                            DING, QILONG

                            Release date:2016-05-17  Release:

                             

                             

                            DING, QILONG

                            Associate Professor of pharmacology

                            Associate Dean of Experimental Center of Pharmacy

                            School of pharmacy

                            Phone: 86-25-86185303

                            Email: dqlcpu@163.com

                            Research Summary

                            Associate Professor DING teaches physiology and pharmacology in CPU. DING’s research focuses on the mechanism of the internal environment imbalance in organism and effects of the imbalance on cardiovascular diseases, such as primary hypertension, hyperlipidemia, atherosclerosis,non-alcoholic fatty liver, insulin resistance and so on, especially reveals mechanisms of redox imbalance causing the diseases and drug intervention. Recently DING and his graduate students are investigating effects and mechanism of redox environment on equilibrium between endothelium-derived relaxing factors (EDRFs) and endothelium-derived constrictingfactors(EDCFs) .The results will give new ideal and principle to treat and prevent hypertension.

                            Education

                            1994-1998  Ph.D., pharmacology, China pharmaceutical University

                            1988-1991  M.S.,  basic medical science, Nanjing Medical University

                            1981-1986  B.S.,   clinical medical science, Tongji Medical University

                            Academic Experience

                            2005-     Associate professor of pharmacology, Experimental Center of Pharmacy

                            1986-2005 Associate professor of pharmacology, Department of Physiology

                            Publications

                            1.Yan S, Zhang X, Zheng H, Hu D, Zhang Y, Guan Q, Liu L, Ding Q(*), Li Y(*).Clematichinenoside inhibits VCAM-1 and ICAM-1 expression in TNF-α-treated endothelial cells via NADPH oxidase-dependent IκB kinase/NF-κB pathway.Free Radic Biol Med. 2015, 78: 190-201.

                            2.Zheng HL, Yan SM, Hu DH, Zhang X, Zhang YT, Guan QH, Ding QL(*)Extracellular redox state regulates catecholamine biosynthesis in PC12 cells with insulin resistance. Hormone and Metabolic Research. 2014, 46(6): 412-8.

                            3.Hu DH, Peng J, Zhang X, Zheng HL, Yan SM, Zhang YT, Guan QH, Ding QL(*).Thyroid hormone exacerbates vasoconstriction in insulin resistance: The role of ONOO-. European Journal of Pharmacology. 2014, 5: 730: 41-50.

                            4.Xu Zhang, Simin Yan, Haili Zheng, Danhong Hu, Yongtian Zhang, Qinghua Guan, Qilong Ding(*). A Mechanism Underlying Hypertensive Occurrence  in the Metabolic Syndrome: Cooperative Effect of  Oxidative Stress and Calcium Accumulation in Vascular Smooth Muscle Cells. Horm Metab Res.2014, 46: 126–132.

                            5.Zhou Y, Lu N, Zhang H, Wei L, Tao L, Dai Q, Zhao L, Lin B, Ding Q(*), Guo Q(*).HQS-3, a newly synthesized flavonoid, possesses potent anti-tumor effect in vivo and in vitro. Eur J Pharm Sci. 2013, 49(4): 649-658.


                             

                                                
                                                

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